Peptocid Oral Suspension 200ml

Side Effects of Peptocid Oral Suspension

• Common: Black stool and black tongue.
• If symptoms persist beyond 2 days, discontinue use and consult a doctor. Do not exceed the recommended dosage.

How does Peptocid Oral Suspension work?

Peptocid 200 ml creates a protective coating for the esophagus and stomach lining. It exerts an anti-diarrheal effect by encouraging the absorption of fluids and electrolytes in the intestines and inhibits prostaglandins responsible for inflammation. Additionally, it binds and neutralizes toxins from harmful bacteria like E. coli, and fights H. pylori infection in the gastrointestinal tract.

Pharmacology:

Antacid Action: Bismuth Subsalicylate coats ulcer surfaces, protecting them from acid and pepsin. It stimulates the secretion of mucus and bicarbonate and reacts with hydrochloric acid (HCl) to produce bismuth oxychloride and salicylic acid, thus reducing stomach acidity.

Anti-Diarrheal Action: Peptocid encourages the absorption of water and electrolytes across the intestinal wall. It also binds to toxins produced by E. coli and disrupts H. pylori cells, preventing their adhesion to the intestinal wall.

Anti-Inflammatory Action: Once hydrolyzed to salicylic acid, Peptocid inhibits prostaglandin synthesis, which reduces inflammation and coats irritated tissue, helping to prevent fluid expulsion.

Overdose Effects

Peptocid overdose may present with symptoms like confusion, tremors, gastrointestinal disturbances, and renal dysfunction. Overdose can also cause salicylate intoxication, leading to symptoms such as dizziness, tinnitus, nausea, and headache. Treatment includes gastric lavage, hydration, and in severe cases, chelation or hemodialysis.

Dosage & Administration:

Adults (over 16): 30 ml using the provided dosing cup or 6 teaspoons.

• Children (10-14 years): 15 ml (3 teaspoons).
• Children (5-9 years): 7.5 ml (1.5 teaspoons).
• Children (3-4 years): 5 ml (1 teaspoon).
• Children under 3 years: Consult a doctor.

Elderly: No special precautions needed.

Renal insufficiency: Use with caution.

Repeat doses can be taken every 30 minutes to 1 hour if needed, but no more than 8 doses should be taken within 24 hours.

Drug Interactions:

Since Peptocid contains salicylates, it should be used cautiously in patients taking:

• Anticoagulants (blood thinners)
• Oral diabetes medications
• Treatments for gout or arthritis

Contraindications:

• Peptocid should not be used by those allergic to aspirin, salicylates, or any other ingredients in this formulation.

Pregnancy & Lactation

Pregnancy Category C: There are insufficient studies in humans to determine the safety of Bismuth Subsalicylate during pregnancy. It should only be used during pregnancy or lactation if necessary.

Precautions & Warnings:

• Avoid taking Peptocid alongside aspirin or other salicylates.
• Caution is required for patients on anticoagulants, or those with diabetes or gout.

Storage:

Store at temperatures below 30°C, away from light and moisture. Keep out of the reach of children.